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SCIENTIFIC SCORE
Questionable
Based on 10 Researches
6.9
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: Two (2) softgels
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Total Carbohydrate
<1 g
<1%**
Vitamin C (as ascorbic acid)
120 mg
133%
Pacran® Whole Fruit Cranberry (Vaccinium macrocarpon)
500 mg
†
Top Medical Research Studies
9
Cranberry juice reduces stone risk
Influence of cranberry juice on the urinary risk factors for calcium oxalate kidney stone formation.
Highly relevant to kidney stones
We explored how cranberry juice, specifically vaccinium macrocarpon, influences the risk factors for developing calcium oxalate kidney stones. In a well-structured study, 20 South African men participated in a randomized cross-over trial. Some of them drank cranberry juice mixed with water for two weeks, while the others consumed only water. After a short break, the two groups switched their drinks to compare results.
Our findings revealed that cranberry juice significantly altered urinary risk factors associated with kidney stones. We observed a decrease in oxalate and phosphate excretion, alongside an increase in citrate excretion. This change resulted in lower relative supersaturation of calcium oxalate compared to just drinking water.
Overall, these results suggest that cranberry juice has potential antilithogenic properties, making it a viable conservative option for managing calcium oxalate kidney stones. Given its influence on urine chemistry, cranberry juice could be considered as part of a preventive strategy against kidney stones.
Our findings revealed that cranberry juice significantly altered urinary risk factors associated with kidney stones. We observed a decrease in oxalate and phosphate excretion, alongside an increase in citrate excretion. This change resulted in lower relative supersaturation of calcium oxalate compared to just drinking water.
Overall, these results suggest that cranberry juice has potential antilithogenic properties, making it a viable conservative option for managing calcium oxalate kidney stones. Given its influence on urine chemistry, cranberry juice could be considered as part of a preventive strategy against kidney stones.
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4
Vitamin C intake risks explored
Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones.
Focused mainly on male participants
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
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9.5
No connection between IVC and stones
No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study.
Study showed no significant findings
We set out to investigate whether high doses of intravenous vitamin C (IVC) could influence the formation of kidney stones. Our study involved 157 adult patients receiving IVC therapy at Integrated Health Options clinic over a 12-month period.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Read More
Most Useful Reviews
9.5
Oxalate count confidence
As a 58-year-old male who suffers from UTIs and kidney stones, I wish I had discovered this product earlier. I just started taking it and hope it prevents my future UTIs. The oxalate count is remarkably low, making it safe for kidney stone sufferers to enjoy the health benefits of cranberry.
Read More
9.5
Symptoms alleviated
I don't use these for UTIs but to soothe my sensitive kidneys and bladder from taking supplements. I need the vitamins but am sensitive to them. After starting this, my symptoms resolved by the next day, allowing me to continue my supplements without excessive irritation. A great price without the added sugar of cranberry juice.
Read More
7.5
Kidney flushing aid
I occasionally suffer from kidney stones and need to keep my kidneys flushed. This product helps with that. It's reasonably priced for what is considered a top brand. Ensure you drink plenty of water for optimal results.
Read More
Most Recommended Products for Kidney Stones
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 10 Researches
6.9
9.5
No connection between IVC and stones
No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study.
Study showed no significant findings
We set out to investigate whether high doses of intravenous vitamin C (IVC) could influence the formation of kidney stones. Our study involved 157 adult patients receiving IVC therapy at Integrated Health Options clinic over a 12-month period.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Read More
9
Cranberry juice reduces stone risk
Influence of cranberry juice on the urinary risk factors for calcium oxalate kidney stone formation.
Highly relevant to kidney stones
We explored how cranberry juice, specifically vaccinium macrocarpon, influences the risk factors for developing calcium oxalate kidney stones. In a well-structured study, 20 South African men participated in a randomized cross-over trial. Some of them drank cranberry juice mixed with water for two weeks, while the others consumed only water. After a short break, the two groups switched their drinks to compare results.
Our findings revealed that cranberry juice significantly altered urinary risk factors associated with kidney stones. We observed a decrease in oxalate and phosphate excretion, alongside an increase in citrate excretion. This change resulted in lower relative supersaturation of calcium oxalate compared to just drinking water.
Overall, these results suggest that cranberry juice has potential antilithogenic properties, making it a viable conservative option for managing calcium oxalate kidney stones. Given its influence on urine chemistry, cranberry juice could be considered as part of a preventive strategy against kidney stones.
Our findings revealed that cranberry juice significantly altered urinary risk factors associated with kidney stones. We observed a decrease in oxalate and phosphate excretion, alongside an increase in citrate excretion. This change resulted in lower relative supersaturation of calcium oxalate compared to just drinking water.
Overall, these results suggest that cranberry juice has potential antilithogenic properties, making it a viable conservative option for managing calcium oxalate kidney stones. Given its influence on urine chemistry, cranberry juice could be considered as part of a preventive strategy against kidney stones.
Read More
8
CDAI may reduce kidney stones
High composite dietary antioxidant index is associated with reduced risk of kidney stones: a cross-sectional analysis of NHANES 2007-2020.
Moderately high relevance to topic
We examined the relationship between dietary antioxidant intake, particularly vitamin C, and the risk of developing kidney stones. Utilizing data from the National Health and Nutrition Examination Survey, we found that individuals with higher levels of antioxidants, as indicated by the Composite Dietary Antioxidant Index (CDAI), had lower odds of forming kidney stones.
Stone formers, those who have experienced kidney stones, typically had a lower CDAI, showcasing significant differences based on gender. An interesting aspect of our findings was that vitamin C stood out as having the strongest negative correlation with kidney stones, suggesting that increased intake may be beneficial.
The results indicated that those in moderate and high CDAI groups had reduced odds of experiencing kidney stones compared to the lowest group. This was reflected in the odds ratios, which showed a significant decrease for those with higher antioxidant consumption. Therefore, it seems that a diet rich in antioxidants, particularly vitamin C, could play a role in lowering kidney stone risks.
However, while our findings are promising, we emphasize the need for more in-depth cohort studies to further investigate this potential connection and confirm its causal nature.
Stone formers, those who have experienced kidney stones, typically had a lower CDAI, showcasing significant differences based on gender. An interesting aspect of our findings was that vitamin C stood out as having the strongest negative correlation with kidney stones, suggesting that increased intake may be beneficial.
The results indicated that those in moderate and high CDAI groups had reduced odds of experiencing kidney stones compared to the lowest group. This was reflected in the odds ratios, which showed a significant decrease for those with higher antioxidant consumption. Therefore, it seems that a diet rich in antioxidants, particularly vitamin C, could play a role in lowering kidney stone risks.
However, while our findings are promising, we emphasize the need for more in-depth cohort studies to further investigate this potential connection and confirm its causal nature.
Read More
8
Vitamin C may reduce kidney stones
Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES).
Highlights vitamin C's specific role
We explored the dietary habits of individuals from the National Health and Nutritional Examination Survey (NHANES) to see how certain foods might influence kidney stone formation.
Our focus was particularly on vitamin C and its potential role in preventing these painful stones. We looked at a diverse group of nearly 17,000 people, analyzing their dietary intake alongside their kidney health over a span of several years.
Interestingly, our findings highlighted a connection between higher vitamin C intake and reduced kidney stone risk. Specifically, we noted that individuals consuming 60 to 110 mg of vitamin C daily had a lower chance of forming stones, with an even greater protective effect observed in those exceeding that amount.
While we didn't find significant associations with many other dietary elements, our results suggest that increasing vitamin C intake might be beneficial. This points towards a need for further research on how vitamin C and other dietary factors interact in the context of kidney stone prevention.
Our focus was particularly on vitamin C and its potential role in preventing these painful stones. We looked at a diverse group of nearly 17,000 people, analyzing their dietary intake alongside their kidney health over a span of several years.
Interestingly, our findings highlighted a connection between higher vitamin C intake and reduced kidney stone risk. Specifically, we noted that individuals consuming 60 to 110 mg of vitamin C daily had a lower chance of forming stones, with an even greater protective effect observed in those exceeding that amount.
While we didn't find significant associations with many other dietary elements, our results suggest that increasing vitamin C intake might be beneficial. This points towards a need for further research on how vitamin C and other dietary factors interact in the context of kidney stone prevention.
Read More
8
Vitamin C formulation lowers oxalate
Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: a preliminary and novel clinical urologic finding.
Addresses kidney stone risk
We examined how different forms of vitamin C affect kidney stones, specifically looking at hyperoxaluria, a key risk factor for stone formation. In our study, conducted as a randomized, double-blind, crossover trial, we compared the effects of traditional ascorbic acid with a formulation containing vitamin C and metabolites, known as Ester-C.
Our findings revealed that Ester-C significantly lowered urine oxalate levels compared to regular ascorbic acid. This is exciting because higher oxalate levels in urine can lead to kidney stones, and finding a formulation that mitigates this risk is important.
Although this study presents promising results, it's essential to note that further evaluation is necessary to fully understand these findings. We believe this is a novel insight into the potential of vitamin C to help prevent kidney stones, and we look forward to additional research in this area.
Our findings revealed that Ester-C significantly lowered urine oxalate levels compared to regular ascorbic acid. This is exciting because higher oxalate levels in urine can lead to kidney stones, and finding a formulation that mitigates this risk is important.
Although this study presents promising results, it's essential to note that further evaluation is necessary to fully understand these findings. We believe this is a novel insight into the potential of vitamin C to help prevent kidney stones, and we look forward to additional research in this area.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Oxalate count confidence
As a 58-year-old male who suffers from UTIs and kidney stones, I wish I had discovered this product earlier. I just started taking it and hope it prevents my future UTIs. The oxalate count is remarkably low, making it safe for kidney stone sufferers to enjoy the health benefits of cranberry.
Read More
9.5
Symptoms alleviated
I don't use these for UTIs but to soothe my sensitive kidneys and bladder from taking supplements. I need the vitamins but am sensitive to them. After starting this, my symptoms resolved by the next day, allowing me to continue my supplements without excessive irritation. A great price without the added sugar of cranberry juice.
Read More
7.5
Kidney flushing aid
I occasionally suffer from kidney stones and need to keep my kidneys flushed. This product helps with that. It's reasonably priced for what is considered a top brand. Ensure you drink plenty of water for optimal results.
